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OPERA: responses to peginterferon and ribavirin therapy in a subgroup of interferon-naïve patients with HIV/HCV genotype 2/3 co-infection in Italy.

Identifieur interne : 000155 ( Main/Exploration ); précédent : 000154; suivant : 000156

OPERA: responses to peginterferon and ribavirin therapy in a subgroup of interferon-naïve patients with HIV/HCV genotype 2/3 co-infection in Italy.

Auteurs : Raffaele Bruno [Italie] ; Giuseppe Cariti ; Paola Nasta ; Amedeo Capetti ; Veronica Ravasio ; Massimo Galli ; Enzo Raise ; Giulio Palmieri ; Claudio Iannacone ; Massimo Puoti

Source :

RBID : pubmed:25041136

Descripteurs français

English descriptors

Abstract

Hepatitis C virus (HCV) genotype 3 (G3) is common among HIV/HCV co-infected individuals and associated with moderate sustained virological response (SVR) rates with pegylated interferon (PEG-IFN) plus ribavirin (RBV) therapy, while G2 is less frequent and associated with higher SVR. To determine SVR and other response rates, identify SVR predictors and analyse differences between G2 and G3 with PEG-IFN/RBV in a large HIV/HCV G2/3 patient population.

DOI: 10.1111/liv.12641
PubMed: 25041136


Affiliations:


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Le document en format XML

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<nlm:affiliation>Department of Infectious Diseases, Hepatology Outpatients Unit University of Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.</nlm:affiliation>
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<wicri:regionArea>Department of Infectious Diseases, Hepatology Outpatients Unit University of Pavia, Fondazione IRCCS Policlinico San Matteo, Pavia</wicri:regionArea>
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<name sortKey="Cariti, Giuseppe" sort="Cariti, Giuseppe" uniqKey="Cariti G" first="Giuseppe" last="Cariti">Giuseppe Cariti</name>
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<name sortKey="Nasta, Paola" sort="Nasta, Paola" uniqKey="Nasta P" first="Paola" last="Nasta">Paola Nasta</name>
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<name sortKey="Capetti, Amedeo" sort="Capetti, Amedeo" uniqKey="Capetti A" first="Amedeo" last="Capetti">Amedeo Capetti</name>
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<name sortKey="Ravasio, Veronica" sort="Ravasio, Veronica" uniqKey="Ravasio V" first="Veronica" last="Ravasio">Veronica Ravasio</name>
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<name sortKey="Galli, Massimo" sort="Galli, Massimo" uniqKey="Galli M" first="Massimo" last="Galli">Massimo Galli</name>
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<name sortKey="Raise, Enzo" sort="Raise, Enzo" uniqKey="Raise E" first="Enzo" last="Raise">Enzo Raise</name>
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<name sortKey="Palmieri, Giulio" sort="Palmieri, Giulio" uniqKey="Palmieri G" first="Giulio" last="Palmieri">Giulio Palmieri</name>
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<name sortKey="Iannacone, Claudio" sort="Iannacone, Claudio" uniqKey="Iannacone C" first="Claudio" last="Iannacone">Claudio Iannacone</name>
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<title level="j">Liver international : official journal of the International Association for the Study of the Liver</title>
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<term>HIV Infections (drug therapy)</term>
<term>Hepacivirus (genetics)</term>
<term>Hepatitis C (complications)</term>
<term>Hepatitis C (drug therapy)</term>
<term>Hepatitis C (genetics)</term>
<term>Humans</term>
<term>Interferon-alpha (therapeutic use)</term>
<term>Italy</term>
<term>Odds Ratio</term>
<term>Polyethylene Glycols (therapeutic use)</term>
<term>Prospective Studies</term>
<term>RNA, Viral (blood)</term>
<term>Recombinant Proteins (therapeutic use)</term>
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<div type="abstract" xml:lang="en">Hepatitis C virus (HCV) genotype 3 (G3) is common among HIV/HCV co-infected individuals and associated with moderate sustained virological response (SVR) rates with pegylated interferon (PEG-IFN) plus ribavirin (RBV) therapy, while G2 is less frequent and associated with higher SVR. To determine SVR and other response rates, identify SVR predictors and analyse differences between G2 and G3 with PEG-IFN/RBV in a large HIV/HCV G2/3 patient population.</div>
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<name sortKey="Galli, Massimo" sort="Galli, Massimo" uniqKey="Galli M" first="Massimo" last="Galli">Massimo Galli</name>
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<name sortKey="Puoti, Massimo" sort="Puoti, Massimo" uniqKey="Puoti M" first="Massimo" last="Puoti">Massimo Puoti</name>
<name sortKey="Raise, Enzo" sort="Raise, Enzo" uniqKey="Raise E" first="Enzo" last="Raise">Enzo Raise</name>
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